Journal of the American College of Cardiology
Volume 49, Issue 25 , Pages 2379-2393 , 26 June 2007

Role of Endothelial Shear Stress in the Natural History of Coronary Atherosclerosis and Vascular Remodeling: Molecular, Cellular, and Vascular Behavior

  • Yiannis S. Chatzizisis, MD, MSc

      Affiliations

    • Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts
    • Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts.
  • ,
  • Ahmet Umit Coskun, PhD

      Affiliations

    • Mechanical and Industrial Engineering, Northeastern University, Boston, Massachusetts
  • ,
  • Michael Jonas, MD

      Affiliations

    • Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts.
  • ,
  • Elazer R. Edelman, MD, PhD, FACC

      Affiliations

    • Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts
    • Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts.
    • Dr. Edelman is receiving a research grant from the National Institutes of Health (R01 HL 49039).
  • ,
  • Charles L. Feldman, ScD

      Affiliations

    • Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts
    • Dr. Feldman receives research grants from Boston Scientific Co. and Novartis Pharmaceutical Co.
  • ,
  • Peter H. Stone, MD, FACC

      Affiliations

    • Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts
    • Dr. Stone receives research grants from Boston Scientific Co., Novartis Pharmaceutical Co., and the National Institutes of Health (NIH).
    • Corresponding Author InformationReprint requests and correspondence: Dr. Peter H. Stone, Cardiovascular Division, Brigham and Women’s Hospital, Harvard Medical School, 75 Francis Street, Boston, Massachusetts.

Received 2 January 2007 ,Revised 22 February 2007 ,Accepted 26 February 2007.

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PII: S0735-1097(07)01220-X

doi: 10.1016/j.jacc.2007.02.059

Journal of the American College of Cardiology
Volume 49, Issue 25 , Pages 2379-2393 , 26 June 2007